9700 AS & A Level Biology: past papers
597 papers from 2008 to 2025, with 64 questions sorted by syllabus topic.
Cell structure Paper 2 · 5 questions
Eukaryotic and prokaryotic cell structure4
Root hair cell structures, and the symplast and apoplast pathways for water crossing the root.
Controlling HIV transmission, magnification, and evidence that the opportunistic pathogen Pneumocystis is a eukaryote (cell wall, organelles).
Organelles of alveolar macrophages, and controlling tuberculosis with BCG vaccination programmes.
Liver blood supply, hepatocyte organelles, Kupffer cells removing old red cells, and peroxisomes vs mitochondria.
Microscopy and magnification2
Controlling HIV transmission, magnification, and evidence that the opportunistic pathogen Pneumocystis is a eukaryote (cell wall, organelles).
Smooth muscle in airways and the gut wall, cell size and magnification, and what a gene mutation is.
Biological molecules Paper 2 · 5 questions
Carbohydrates and lipids2
Galactose compared with α-glucose, and analysing sugar content data for carrot varieties.
Fatty acids in olive oil: saturated and unsaturated chains, and the structure and variety of triglycerides.
Proteins and water3
Haemoglobin as a globular protein, and the substances involved in carrying oxygen and carbon dioxide in blood.
Using photosynthesis products, nitrate uptake by roots, and loading amino acids and sucrose into phloem.
Keratin structure with disulfide bonds, and comparing keratinase enzymes for temperature and pH range.
Enzymes Paper 2 · 3 questions
Enzyme action and kinetics3
Non-competitive inhibition and Km for horseradish peroxidase, and start and stop codons in a synthetic gene.
Lysozyme and the induced-fit model, and comparing lysozyme with penicillin as antibacterial agents.
Keratin structure with disulfide bonds, and comparing keratinase enzymes for temperature and pH range.
Cell membranes and transport Paper 2 · 3 questions
Transport across membranes3
The apoplast pathway and the Casparian strip, and active transport vs facilitated diffusion of potassium ions into root cells.
Using photosynthesis products, nitrate uptake by roots, and loading amino acids and sucrose into phloem.
Maintaining diffusion gradients in alveoli, ventilation, surfactant, and transcription and translation of a transporter gene.
The mitotic cell cycle Paper 2 · 4 questions
Mitosis and the cell cycle4
Using antibodies on magnetic beads to collect stem cells, and making artificial red blood cells.
Adult stem cells, tissue repair by mitosis, tumour formation, telomeres, and blood cells formed from bone marrow stem cells.
Chromatin condensing into chromosomes during mitosis.
Chromatin and histones, chromosome structure at metaphase, and changes to chromosomes from S phase through mitosis.
Nucleic acids and protein synthesis Paper 2 · 4 questions
DNA structure and replication1
Complementary base pairing between DNA and RNA nucleotides during transcription.
Transcription and translation4
Non-competitive inhibition and Km for horseradish peroxidase, and start and stop codons in a synthetic gene.
Complementary base pairing between DNA and RNA nucleotides during transcription.
Smooth muscle in airways and the gut wall, cell size and magnification, and what a gene mutation is.
Maintaining diffusion gradients in alveoli, ventilation, surfactant, and transcription and translation of a transporter gene.
Transport in plants Paper 2 · 4 questions
Xylem, phloem and transpiration4
Root hair cell structures, and the symplast and apoplast pathways for water crossing the root.
The apoplast pathway and the Casparian strip, and active transport vs facilitated diffusion of potassium ions into root cells.
Using photosynthesis products, nitrate uptake by roots, and loading amino acids and sucrose into phloem.
Xylem vessel elements, cohesion-tension, and how xylem structure reduces resistance to flow.
Transport in mammals Paper 2 · 5 questions
Blood vessels and haemoglobin4
Haemoglobin as a globular protein, and the substances involved in carrying oxygen and carbon dioxide in blood.
Malaria and the oxygen dissociation curve: standardising an experiment and the effect of a right shift on loading and unloading.
Liver blood supply, hepatocyte organelles, Kupffer cells removing old red cells, and peroxisomes vs mitochondria.
Tuberculosis species and transmission between people and animals, and spread to arteries.
The heart and cardiac cycle1
HIV/AIDS and antiretroviral therapy, and a coronary artery bypass graft.
Gas exchange Paper 2 · 3 questions
Gas exchange surfaces3
Tuberculosis: the pathogen, transmission, antibiotic treatment, and identifying airways and blood vessels in lung tissue.
Smooth muscle in airways and the gut wall, cell size and magnification, and what a gene mutation is.
Maintaining diffusion gradients in alveoli, ventilation, surfactant, and transcription and translation of a transporter gene.
Infectious diseases Paper 2 · 7 questions
Infectious diseases and antibiotics7
Tuberculosis: the pathogen, transmission, antibiotic treatment, and identifying airways and blood vessels in lung tissue.
Controlling HIV transmission, magnification, and evidence that the opportunistic pathogen Pneumocystis is a eukaryote (cell wall, organelles).
Malaria and the oxygen dissociation curve: standardising an experiment and the effect of a right shift on loading and unloading.
Organelles of alveolar macrophages, and controlling tuberculosis with BCG vaccination programmes.
Lysozyme and the induced-fit model, and comparing lysozyme with penicillin as antibacterial agents.
HIV/AIDS and antiretroviral therapy, and a coronary artery bypass graft.
Tuberculosis species and transmission between people and animals, and spread to arteries.
Immunity Paper 2 · 3 questions
Immune response and vaccination3
Using antibodies on magnetic beads to collect stem cells, and making artificial red blood cells.
Adult stem cells, tissue repair by mitosis, tumour formation, telomeres, and blood cells formed from bone marrow stem cells.
Organelles of alveolar macrophages, and controlling tuberculosis with BCG vaccination programmes.